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Renal Medullary Carcinomas Harbor a Distinct Methylation Phenotype and Display Aberrant Methylation of Genes Related to Early Nephrogenesis

SIMPLE SUMMARY: Renal medullary carcinomas (RMC) are aggressive tumors of the kidneys, characterized by a loss of SMARCB1. As the tumors, arising predominantly in young males with sickle cell trait, are very rare and no standard method for detection or treatment has been described, prognosis for the...

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Detalles Bibliográficos
Autores principales: Fincke, Victoria E., Krulik, Mateja E., Joshi, Piyush, Frühwald, Michael C., Chen, Ying-Bei, Johann, Pascal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599670/
https://www.ncbi.nlm.nih.gov/pubmed/36291828
http://dx.doi.org/10.3390/cancers14205044