Immune-Checkpoint Inhibitors (ICIs) in Metastatic Colorectal Cancer (mCRC) Patients beyond Microsatellite Instability

SIMPLE SUMMARY: The manuscript reports the most recent literature regarding treatment with ICIs in mCRC, focusing on dMMR/MSI-H and POLE-mutated tumors, discussing current knowledge and potential hypotheses about molecular and/or clinical features related to intrinsic and secondary resistance to ICI...

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Detalles Bibliográficos
Autores principales: Borelli, Beatrice, Antoniotti, Carlotta, Carullo, Martina, Germani, Marco Maria, Conca, Veronica, Masi, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599678/
https://www.ncbi.nlm.nih.gov/pubmed/36291761
http://dx.doi.org/10.3390/cancers14204974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599678/
https://www.ncbi.nlm.nih.gov/pubmed/36291761
http://dx.doi.org/10.3390/cancers14204974

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