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Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia

The brain is susceptible to perturbations of redox balance, affecting neurogenesis and increasing the risks of psychiatric disorders. Thioredoxin-interacting protein (TXNIP) is an endogenous inhibitor of the thioredoxin antioxidant system. Its deletion or inhibition suggests protection for a brain w...

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Detalles Bibliográficos
Autores principales: Xue, Ting, Wang, Xiaodan, Hu, Ying, Cheng, Ying, Li, Han, Shi, Yuan, Wang, Lijun, Yin, Dongmin, Cui, Donghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599691/
https://www.ncbi.nlm.nih.gov/pubmed/36291328
http://dx.doi.org/10.3390/brainsci12101395