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Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia
The brain is susceptible to perturbations of redox balance, affecting neurogenesis and increasing the risks of psychiatric disorders. Thioredoxin-interacting protein (TXNIP) is an endogenous inhibitor of the thioredoxin antioxidant system. Its deletion or inhibition suggests protection for a brain w...
Autores principales: | Xue, Ting, Wang, Xiaodan, Hu, Ying, Cheng, Ying, Li, Han, Shi, Yuan, Wang, Lijun, Yin, Dongmin, Cui, Donghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599691/ https://www.ncbi.nlm.nih.gov/pubmed/36291328 http://dx.doi.org/10.3390/brainsci12101395 |
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