Ferroptosis Induction and YAP Inhibition as New Therapeutic Targets in Gastrointestinal Stromal Tumors (GISTs)

SIMPLE SUMMARY: Despite targeted therapy with tyrosine kinase inhibitors (TKIs), unresectable or metastatic human GISTs generally relapse under treatment. Thus, alternative therapeutic approaches are needed to overcome GIST resistance. Ferroptosis, a cell death driven by iron-dependent phospholipid...

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Detalles Bibliográficos
Autores principales: Delvaux, Marine, Hagué, Perrine, Craciun, Ligia, Wozniak, Agnieszka, Demetter, Pieter, Schöffski, Patrick, Erneux, Christophe, Vanderwinden, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599726/
https://www.ncbi.nlm.nih.gov/pubmed/36291834
http://dx.doi.org/10.3390/cancers14205050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599726/
https://www.ncbi.nlm.nih.gov/pubmed/36291834
http://dx.doi.org/10.3390/cancers14205050

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