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Common Mechanism of Activated Catalysis in P-loop Fold Nucleoside Triphosphatases—United in Diversity

To clarify the obscure hydrolysis mechanism of ubiquitous P-loop-fold nucleoside triphosphatases (Walker NTPases), we analysed the structures of 3136 catalytic sites with bound Mg-NTP complexes or their analogues. Our results are presented in two articles; here, in the second of them, we elucidated...

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Detalles Bibliográficos
Autores principales: Kozlova, Maria I., Shalaeva, Daria N., Dibrova, Daria V., Mulkidjanian, Armen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599734/
https://www.ncbi.nlm.nih.gov/pubmed/36291556
http://dx.doi.org/10.3390/biom12101346