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Association of SLC22A1, SLC22A2, SLC47A1, and SLC47A2 Polymorphisms with Metformin Efficacy in Type 2 Diabetic Patients

Response to metformin, first-line therapy for type 2 diabetes mellitus (T2DM), exists interindividual variation. Considering that transporters belonging to the solute carrier (SLC) superfamily are determinants of metformin pharmacokinetics, we evaluated the effects of promoter variants in organic ca...

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Detalles Bibliográficos
Autores principales: Chen, Peixian, Cao, Yumin, Chen, Shenren, Liu, Zhike, Chen, Shiyi, Guo, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599747/
https://www.ncbi.nlm.nih.gov/pubmed/36289808
http://dx.doi.org/10.3390/biomedicines10102546