Computational Dissection of the Role of Trp305 in the Regulation of the Death-Associated Protein Kinase–Calmodulin Interaction

Death-associated protein kinase 1 (DAPK1), as a calcium/calmodulin (CaM) regulated serine/threonine kinase, functions in apoptotic and autophagy pathways and represents an interesting drug target for inflammatory bowel disease and Alzheimer’s disease. The crystal structure of the DAPK1 catalytic dom...

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Detalles Bibliográficos
Autores principales: Zhu, Yu-Ping, Gao, Xin-Yi, Xu, Guo-Hui, Qin, Zhao-Fu, Ju, Hai-Xing, Li, De-Chuan, Ma, De-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599780/
https://www.ncbi.nlm.nih.gov/pubmed/36291604
http://dx.doi.org/10.3390/biom12101395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599780/
https://www.ncbi.nlm.nih.gov/pubmed/36291604
http://dx.doi.org/10.3390/biom12101395

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