Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity

The gut peptide, ghrelin, mediates energy homeostasis and reproduction by acting through its receptor, growth hormone secretagogue receptor (GHSR), expressed in hypothalamic neurons in the arcuate (ARC). We have shown 17β-estradiol (E2) increases Ghsr expression in Kisspeptin/Neurokinin B/Dynorphin...

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Detalles Bibliográficos
Autores principales: Conde, Kristie, Kulyk, Danielle, Vanschaik, Allison, Daisey, Sierra, Rojas, Catherine, Wiersielis, Kimberly, Yasrebi, Ali, Degroat, Thomas J., Sun, Yuxiang, Roepke, Troy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599822/
https://www.ncbi.nlm.nih.gov/pubmed/36291579
http://dx.doi.org/10.3390/biom12101370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599822/
https://www.ncbi.nlm.nih.gov/pubmed/36291579
http://dx.doi.org/10.3390/biom12101370

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