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Inhibition of Phosphoglycerate Dehydrogenase Radiosensitizes Human Colorectal Cancer Cells under Hypoxic Conditions

SIMPLE SUMMARY: Colorectal cancer is the third most prevalent cancer worldwide. Treatment options for these patients consist of surgery combined with chemotherapy and/or radiotherapy. However, a subset of tumors will not respond to therapy or acquire resistance during the course of the treatment, le...

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Detalles Bibliográficos
Autores principales: Van de Gucht, Melissa, Dufait, Inès, Kerkhove, Lisa, Corbet, Cyril, de Mey, Sven, Jiang, Heng, Law, Ka Lun, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599856/
https://www.ncbi.nlm.nih.gov/pubmed/36291844
http://dx.doi.org/10.3390/cancers14205060