Modeling Reactive Oxygen Species-Induced Axonal Loss in Leber Hereditary Optic Neuropathy

Leber hereditary optic neuropathy (LHON) is a rare syndrome that results in vision loss. A necessary but not sufficient condition for its onset is the existence of known mitochondrial DNA mutations that affect complex I biomolecular structure. Cybrids with LHON mutations generate higher rates of rea...

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Detalles Bibliográficos
Autores principales: Lambiri, Darius W., Levin, Leonard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599876/
https://www.ncbi.nlm.nih.gov/pubmed/36291620
http://dx.doi.org/10.3390/biom12101411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599876/
https://www.ncbi.nlm.nih.gov/pubmed/36291620
http://dx.doi.org/10.3390/biom12101411

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