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Correlation of Yes-Associated Protein 1 with Stroma Type and Tumor Stiffness in Hormone-Receptor Positive Breast Cancer

SIMPLE SUMMARY: YAP1 is an oncogene that can be activated by matrix stiffness, as it can act as a mechanotransducer. So far, only in vitro studies regarding YAP1 activation and matrix stiffness are present. We confirmed the activation of YAP1 in breast cancer using human breast cancer tissue and imm...

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Detalles Bibliográficos
Autores principales: Lee, Yangkyu, Bae, Soong June, Eun, Na Lae, Ahn, Sung Gwe, Jeong, Joon, Cha, Yoon Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599900/
https://www.ncbi.nlm.nih.gov/pubmed/36291755
http://dx.doi.org/10.3390/cancers14204971