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Blast Exposure Dysregulates Nighttime Melatonin Synthesis and Signaling in the Pineal Gland: A Potential Mechanism of Blast-Induced Sleep Disruptions

Blast-induced traumatic brain injury (bTBI) frequently results in sleep-wake disturbances. However, limited studies have investigated the molecular signaling mechanisms underlying these sleep disturbances, and potentially efficacious therapies are lacking. We investigated the levels of melatonin and...

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Detalles Bibliográficos
Autores principales: Govindarajulu, Manoj, Patel, Mital Y., Wilder, Donna M., Long, Joseph B., Arun, Peethambaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599907/
https://www.ncbi.nlm.nih.gov/pubmed/36291274
http://dx.doi.org/10.3390/brainsci12101340