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Blast Exposure Dysregulates Nighttime Melatonin Synthesis and Signaling in the Pineal Gland: A Potential Mechanism of Blast-Induced Sleep Disruptions
Blast-induced traumatic brain injury (bTBI) frequently results in sleep-wake disturbances. However, limited studies have investigated the molecular signaling mechanisms underlying these sleep disturbances, and potentially efficacious therapies are lacking. We investigated the levels of melatonin and...
Autores principales: | Govindarajulu, Manoj, Patel, Mital Y., Wilder, Donna M., Long, Joseph B., Arun, Peethambaran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599907/ https://www.ncbi.nlm.nih.gov/pubmed/36291274 http://dx.doi.org/10.3390/brainsci12101340 |
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