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Molecularly Targeted Photothermal Ablation of Epidermal Growth Factor Receptor-Expressing Cancer Cells with a Polypyrrole–Iron Oxide–Afatinib Nanocomposite

SIMPLE SUMMARY: In this manuscript, we describe the design and synthesis of a nanocomposite containing afatinib, polypyrrole, and iron oxide (PIA-NC) to molecularly target epidermal growth factor receptor (EGFR)-overexpressing cancer cells for photothermal conversion. In addition to physical and che...

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Detalles Bibliográficos
Autores principales: Rethi, Lekshmi, Mutalik, Chinmaya, Rethi, Lekha, Chiang, Wei-Hung, Lee, Hsin-Lun, Pan, Wen-Yu, Yang, Tze-Sen, Chiou, Jeng-Fong, Chen, Yin-Ju, Chuang, Er-Yuan, Lu, Long-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599920/
https://www.ncbi.nlm.nih.gov/pubmed/36291827
http://dx.doi.org/10.3390/cancers14205043