A Programmable, DNA-Exclusively-Guided Argonaute DNase and Its Higher Cleavage Specificity Achieved by 5′-Hydroxylated Guide

Argonaute proteins exist widely in eukaryotes and prokaryotes, and they are of great potential for molecular cloning, nucleic acid detection, DNA assembly, and gene editing. However, their overall properties are not satisfactory and hinder their broad applications. Herein, we investigated a prokaryo...

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Detalles Bibliográficos
Autores principales: Sun, Shichao, Xu, Dejin, Zhu, Lin, Hu, Bei, Huang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599953/
https://www.ncbi.nlm.nih.gov/pubmed/36291549
http://dx.doi.org/10.3390/biom12101340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599953/
https://www.ncbi.nlm.nih.gov/pubmed/36291549
http://dx.doi.org/10.3390/biom12101340

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