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Inhibition of the Cell Uptake of Delta and Omicron SARS-CoV-2 Pseudoviruses by N-Acetylcysteine Irrespective of the Oxidoreductive Environment

The binding of SARS-CoV-2 spikes to the cell receptor angiotensin-converting enzyme 2 (ACE2) is a crucial target both in the prevention and in the therapy of COVID-19. We explored the involvement of oxidoreductive mechanisms by investigating the effects of oxidants and antioxidants on virus uptake b...

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Detalles Bibliográficos
Autores principales: La Maestra, Sebastiano, Garibaldi, Silvano, Balansky, Roumen, D’Agostini, Francesco, Micale, Rosanna T., De Flora, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599975/
https://www.ncbi.nlm.nih.gov/pubmed/36291178
http://dx.doi.org/10.3390/cells11203313