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Mannose and Hyaluronic Acid Dual-Modified Iron Oxide Enhances Neoantigen-Based Peptide Vaccine Therapy by Polarizing Tumor-Associated Macrophages

SIMPLE SUMMARY: Cancer vaccine therapy is promising, though its efficacy is compromised in an immunosuppressive tumor microenvironment. Tumor-associated macrophages (TAMs) have the potential to be repolarized to an antitumor subtype, and their antigen-presenting ability might enhance the efficacy of...

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Detalles Bibliográficos
Autores principales: Nie, Ying, Shi, Lu, Zhang, Yanan, Guo, Yunfei, Gu, Hongchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599981/
https://www.ncbi.nlm.nih.gov/pubmed/36291890
http://dx.doi.org/10.3390/cancers14205107