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Pro-Inflammatory and Pro-Apoptotic Effects of the Non-Protein Amino Acid L-Azetidine-2-Carboxylic Acid in BV2 Microglial Cells

L-Azetidine-2-carboxylic acid (AZE) is a toxic non-protein coding amino acid (npAA) that is highly abundant in sugar and table beets. Due to its structural similarity with the amino acid L-proline, AZE can evade the editing process during protein assembly in eukaryotic cells and be misincorporated i...

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Detalles Bibliográficos
Autores principales: Piper, Jordan Allan, Jansen, Margo Iris, Thomas Broome, Sarah, Rodgers, Kenneth J., Musumeci, Giuseppe, Castorina, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600089/
https://www.ncbi.nlm.nih.gov/pubmed/36286023
http://dx.doi.org/10.3390/cimb44100308