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Pro-Inflammatory and Pro-Apoptotic Effects of the Non-Protein Amino Acid L-Azetidine-2-Carboxylic Acid in BV2 Microglial Cells
L-Azetidine-2-carboxylic acid (AZE) is a toxic non-protein coding amino acid (npAA) that is highly abundant in sugar and table beets. Due to its structural similarity with the amino acid L-proline, AZE can evade the editing process during protein assembly in eukaryotic cells and be misincorporated i...
Autores principales: | Piper, Jordan Allan, Jansen, Margo Iris, Thomas Broome, Sarah, Rodgers, Kenneth J., Musumeci, Giuseppe, Castorina, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600089/ https://www.ncbi.nlm.nih.gov/pubmed/36286023 http://dx.doi.org/10.3390/cimb44100308 |
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