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Reduction in SOCE and Associated Aggregation in Platelets from Mice with Platelet-Specific Deletion of Orai1

Calcium signalling in platelets through store operated Ca(2+) entry (SOCE) or receptor-operated Ca(2+) entry (ROCE) mechanisms is crucial for platelet activation and function. Orai1 proteins have been implicated in platelet’s SOCE. In this study we evaluated the contribution of Orai1 proteins to the...

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Detalles Bibliográficos
Autores principales: Yang, Linlin, Ottenheijm, Roger, Worley, Paul, Freichel, Marc, Camacho Londoño, Juan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600098/
https://www.ncbi.nlm.nih.gov/pubmed/36291093
http://dx.doi.org/10.3390/cells11203225