Rotavirus Downregulates Tyrosine Hydroxylase in the Noradrenergic Sympathetic Nervous System in Ileum, Early in Infection and Simultaneously with Increased Intestinal Transit and Altered Brain Activities

While rotavirus diarrhea has been considered to occur only due to intrinsic intestinal effects within the enteric nervous system, we provide evidence for central nervous system control underlying the clinical symptomology. Our data visualize infection by large-scale three-dimensional (3D) volumetric...

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Detalles Bibliográficos
Autores principales: Hellysaz, Arash, Svensson, Lennart, Hagbom, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600178/
https://www.ncbi.nlm.nih.gov/pubmed/36094089
http://dx.doi.org/10.1128/mbio.01387-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600178/
https://www.ncbi.nlm.nih.gov/pubmed/36094089
http://dx.doi.org/10.1128/mbio.01387-22

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