Vaccination with Live or Heat-Killed Aspergillus fumigatus ΔsglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis

Aspergillus fumigatus causes invasive aspergillosis (IA) in immunocompromised patients, resulting in high mortality rates. Currently, no vaccine formulations to promote immune protection in at-risk individuals have been developed. In this work, we deleted the sterylglucosidase-encoding gene, sglA, i...

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Detalles Bibliográficos
Autores principales: Fernandes, Caroline Mota, Normile, Tyler G., Fabri, Joao Henrique Tadini Marilhano, Brauer, Veronica Soares, de S. Araújo, Glauber R., Frases, Susana, Nimrichter, Leonardo, Malavazi, Iran, Del Poeta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600187/
https://www.ncbi.nlm.nih.gov/pubmed/36066100
http://dx.doi.org/10.1128/mbio.02328-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600187/
https://www.ncbi.nlm.nih.gov/pubmed/36066100
http://dx.doi.org/10.1128/mbio.02328-22

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