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Low Nephron Number Induced by Maternal Protein Restriction Is Prevented by Nicotinamide Riboside Supplementation Depending on Sirtuin 3 Activation

A reduced nephron number at birth, due to critical gestational conditions, including maternal malnutrition, is associated with the risk of developing hypertension and chronic kidney disease in adulthood. No interventions are currently available to augment nephron number. We have recently shown that...

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Detalles Bibliográficos
Autores principales: Pezzotta, Anna, Perico, Luca, Morigi, Marina, Corna, Daniela, Locatelli, Monica, Zoja, Carlamaria, Benigni, Ariela, Remuzzi, Giuseppe, Imberti, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600228/
https://www.ncbi.nlm.nih.gov/pubmed/36291179
http://dx.doi.org/10.3390/cells11203316