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The C-Terminus of the PSMA3 Proteasome Subunit Preferentially Traps Intrinsically Disordered Proteins for Degradation

The degradation of intrinsically disordered proteins (IDPs) by a non-26S proteasome process does not require proteasomal targeting by polyubiquitin. However, whether and how IDPs are recognized by the non-26S proteasome, including the 20S complex, remains unknown. Analyses of protein interactome dat...

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Detalles Bibliográficos
Autores principales: Biran, Assaf, Myers, Nadav, Steinberger, Shirel, Adler, Julia, Riutin, Marianna, Broennimann, Karin, Reuven, Nina, Shaul, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600399/
https://www.ncbi.nlm.nih.gov/pubmed/36291102
http://dx.doi.org/10.3390/cells11203231