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Advances and Hurdles in CAR T Cell Immune Therapy for Solid Tumors

SIMPLE SUMMARY: Chimeric antigen receptor (CAR) T cells are genetically engineered T cells that recognize markers present on tumor cells and drive the degradation of the tumor itself. CAR T immunotherapy has obtained remarkable success in targeting a number of blood malignancies; however, its outcom...

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Detalles Bibliográficos
Autores principales: Boccalatte, Francesco, Mina, Roberto, Aroldi, Andrea, Leone, Sarah, Suryadevara, Carter M., Placantonakis, Dimitris G., Bruno, Benedetto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600451/
https://www.ncbi.nlm.nih.gov/pubmed/36291891
http://dx.doi.org/10.3390/cancers14205108