Lack of Retinoblastoma Protein Shifts Tumor Metabolism from Glycolysis to OXPHOS and Allows the Use of Alternate Fuels

Mutations in the RB1 locus leading to a loss of functional Rb protein cause intraocular tumors, which uniquely affect children worldwide. These tumors demonstrate rapid proliferation, which has recently been shown to be associated with an altered metabolic signature. We found that retinoblastoma tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Suresh Babu, Vishnu, Dudeja, Gagan, SA, Deepak, Bisht, Anadi, Shetty, Rohit, Heymans, Stephane, Guha, Nilanjan, Ghosh, Arkasubhra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600484/
https://www.ncbi.nlm.nih.gov/pubmed/36291051
http://dx.doi.org/10.3390/cells11203182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600484/
https://www.ncbi.nlm.nih.gov/pubmed/36291051
http://dx.doi.org/10.3390/cells11203182

Ejemplares similares