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Distinct Mechanisms of Target Search by Endonuclease VIII-like DNA Glycosylases

Proteins that recognize specific DNA sequences or structural elements often find their cognate DNA lesions in a processive mode, in which an enzyme binds DNA non-specifically and then slides along the DNA contour by one-dimensional diffusion. Opposite to the processive mechanism is distributive sear...

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Detalles Bibliográficos
Autores principales: Diatlova, Evgeniia A., Mechetin, Grigory V., Zharkov, Dmitry O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600533/
https://www.ncbi.nlm.nih.gov/pubmed/36291061
http://dx.doi.org/10.3390/cells11203192