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Redox-Mediated Inactivation of the Transcriptional Repressor RcrR is Responsible for Uropathogenic Escherichia coli’s Increased Resistance to Reactive Chlorine Species

The ability to overcome stressful environments is critical for pathogen survival in the host. One challenge for bacteria is the exposure to reactive chlorine species (RCS), which are generated by innate immune cells as a critical part of the oxidative burst. Hypochlorous acid (HOCl) is the most pote...

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Detalles Bibliográficos
Autores principales: Sultana, Sadia, Crompton, Mary E., Meurer, Kennadi, Jankiewicz, Olivia, Morales, Grace H., Johnson, Colton, Horbach, Elise, Hoffmann, Kevin Pierre, Kr, Pooja, Shah, Ritika, Anderson, Greg M., Mortimer, Nathan T., Schmitz, Jonathan E., Hadjifrangiskou, Maria, Foti, Alessandro, Dahl, Jan-Ulrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600549/
https://www.ncbi.nlm.nih.gov/pubmed/36073817
http://dx.doi.org/10.1128/mbio.01926-22