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High-Affinity Cu(I)-Chelator with Potential Anti-Tumorigenic Action—A Proof-of-Principle Experimental Study of Human H460 Tumors in the CAM Assay

SIMPLE SUMMARY: Lung cancer is a serious burden worldwide. The growth of lung tumors depends on vessel density and intratumoral copper concentration. Copper chelating agents can reduce copper content in tumor tissue, resulting in lower vessel density and lower tumor weight. PSP-2, a very potent copp...

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Detalles Bibliográficos
Autores principales: Heuberger, Dorothea M., Wolint, Petra, Jang, Jae-Hwi, Itani, Saria, Jungraithmayr, Wolfgang, Waschkies, Conny F., Meier-Bürgisser, Gabriella, Andreoli, Stefano, Spanaus, Katharina, Schuepbach, Reto A., Calcagni, Maurizio, Fahrni, Christoph J., Buschmann, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600560/
https://www.ncbi.nlm.nih.gov/pubmed/36291910
http://dx.doi.org/10.3390/cancers14205122