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Cobalamin Riboswitches Are Broadly Sensitive to Corrinoid Cofactors to Enable an Efficient Gene Regulatory Strategy

In bacteria, many essential metabolic processes are controlled by riboswitches, gene regulatory RNAs that directly bind and detect metabolites. Highly specific effector binding enables riboswitches to respond to a single biologically relevant metabolite. Cobalamin riboswitches are a potential except...

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Detalles Bibliográficos
Autores principales: Kennedy, Kristopher J., Widner, Florian J., Sokolovskaya, Olga M., Innocent, Lina V., Procknow, Rebecca R., Mok, Kenny C., Taga, Michiko E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600662/
https://www.ncbi.nlm.nih.gov/pubmed/35993747
http://dx.doi.org/10.1128/mbio.01121-22