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Induction of Breast Cancer Cell Apoptosis by TRAIL and Smac Mimetics: Involvement of RIP1 and cFLIP

Smac mimetics are a group of compounds able to facilitate cell death in cancer cells. TNF-related apoptosis-inducing ligand (TRAIL) is a death receptor ligand currently explored in combination with Smac mimetics. The molecular mechanisms determining if the combination treatment results in apoptosis...

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Detalles Bibliográficos
Autores principales: Holmgren, Christian, Sunström Thörnberg, Ellen, Granqvist, Victoria, Larsson, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600666/
https://www.ncbi.nlm.nih.gov/pubmed/36286042
http://dx.doi.org/10.3390/cimb44100327