Uncovering Lasonolide A Biosynthesis Using Genome-Resolved Metagenomics

Invertebrates, particularly sponges, have been a dominant source of new marine natural products. For example, lasonolide A (LSA) is a potential anticancer molecule isolated from the marine sponge Forcepia sp., with nanomolar growth inhibitory activity and a unique cytotoxicity profile against the Na...

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Detalles Bibliográficos
Autores principales: Uppal, Siddharth, Metz, Jackie L., Xavier, René K. M., Nepal, Keshav Kumar, Xu, Dongbo, Wang, Guojun, Kwan, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600693/
https://www.ncbi.nlm.nih.gov/pubmed/36125273
http://dx.doi.org/10.1128/mbio.01524-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600693/
https://www.ncbi.nlm.nih.gov/pubmed/36125273
http://dx.doi.org/10.1128/mbio.01524-22

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