Cargando…

Uncovering Lasonolide A Biosynthesis Using Genome-Resolved Metagenomics

Invertebrates, particularly sponges, have been a dominant source of new marine natural products. For example, lasonolide A (LSA) is a potential anticancer molecule isolated from the marine sponge Forcepia sp., with nanomolar growth inhibitory activity and a unique cytotoxicity profile against the Na...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uppal, Siddharth, Metz, Jackie L., Xavier, René K. M., Nepal, Keshav Kumar, Xu, Dongbo, Wang, Guojun, Kwan, Jason C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600693/ https://www.ncbi.nlm.nih.gov/pubmed/36125273 http://dx.doi.org/10.1128/mbio.01524-22

Ejemplares similares

Activation of RAF1 (c-RAF) by the Marine Alkaloid Lasonolide A Induces Rapid Premature Chromosome Condensation
por: Jossé, Rozenn, et al.
Publicado: (2015)

Stable-Isotope-Informed, Genome-Resolved Metagenomics Uncovers Potential Cross-Kingdom Interactions in Rhizosphere Soil
por: Starr, Evan P., et al.
Publicado: (2021)

Genome-resolved metagenomics of sugarcane vinasse bacteria
por: Cassman, Noriko A., et al.
Publicado: (2018)

Advancing Genome-Resolved Metagenomics beyond the Shotgun
por: Malmstrom, Rex R., et al.
Publicado: (2019)

Genome-Resolved Metagenomics of the Chicken Gut Microbiome
por: Segura-Wang, Maia, et al.
Publicado: (2021)

MAGNETO: An Automated Workflow for Genome-Resolved Metagenomics
por: Churcheward, Benjamin, et al.
Publicado: (2022)

Unlocking a new target for streptomycetes strain improvement
por: Chen, Yuan, et al.
Publicado: (2020)

Correction to: Genome-resolved metagenomics of sugarcane vinasse bacteria
por: Cassman, Noriko A., et al.
Publicado: (2018)

Applying Genome-Resolved Metagenomics to Deconvolute the Halophilic Microbiome
por: Uritskiy, Gherman, et al.
Publicado: (2019)

Genome-resolved metagenomics using environmental and clinical samples
por: Kayani, Masood ur Rehman, et al.
Publicado: (2021)

Metagenome-assembled genomes uncover a global brackish microbiome
por: Hugerth, Luisa W., et al.
Publicado: (2015)

Novel diversity of polar Cyanobacteria revealed by genome-resolved metagenomics
por: Pessi, Igor S., et al.
Publicado: (2023)

Uncovering the genomic and metagenomic research potential in old ethanol-preserved snakes
por: Zacho, Claus M., et al.
Publicado: (2021)

Protein Language Models Uncover Carbohydrate-Active Enzyme Function in Metagenomics
por: Thurimella, Kumar, et al.
Publicado: (2023)

A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
por: Wang, Chao, et al.
Publicado: (2021)

BugSplit enables genome-resolved metagenomics through highly accurate taxonomic binning of metagenomic assemblies
por: Chandrakumar, Induja, et al.
Publicado: (2022)

Functional metagenomics uncovers nitrile-hydrolysing enzymes in a coal metagenome
por: Achudhan, Arunmozhi Bharathi, et al.
Publicado: (2023)

On the Road to Strain-Resolved Comparative Metagenomics
por: Segata, Nicola
Publicado: (2018)

Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp. HB-J378
por: Xu, Dongbo, et al.
Publicado: (2018)

Recovering Genomics Clusters of Secondary Metabolites from Lakes Using Genome-Resolved Metagenomics
por: Cuadrat, Rafael R. C., et al.
Publicado: (2018)

MetaWRAP—a flexible pipeline for genome-resolved metagenomic data analysis
por: Uritskiy, Gherman V., et al.
Publicado: (2018)

Genome-Resolved Metagenomics of a Photosynthetic Bioreactor Performing Biological Nutrient Removal
por: McDaniel, Elizabeth A., et al.
Publicado: (2021)

Functional Insights of Salinity Stress-Related Pathways in Metagenome-Resolved Methanothrix Genomes
por: Gagliano, Maria Cristina, et al.
Publicado: (2022)

Metagenomic methylation patterns resolve bacterial genomes of unusual size and structural complexity
por: Wilbanks, Elizabeth G., et al.
Publicado: (2022)

Is metagenomics resolving identification of functions in microbial communities?
por: Chistoserdova, Ludmila
Publicado: (2014)

Genome Sequence of Streptomyces sp. Strain HB-N217, Isolated from the Marine Sponge Forcepia sp.
por: Xavier, René K. M., et al.
Publicado: (2021)

Resolving Prokaryotic Taxonomy without rRNA: Longer Oligonucleotide Word Lengths Improve Genome and Metagenome Taxonomic Classification
por: Alsop, Eric B., et al.
Publicado: (2013)

Tracking microbial colonization in fecal microbiota transplantation experiments via genome-resolved metagenomics
por: Lee, Sonny T. M., et al.
Publicado: (2017)

Genome-Resolved Metagenomics Extends the Environmental Distribution of the Verrucomicrobia Phylum to the Deep Terrestrial Subsurface
por: Nixon, Sophie L., et al.
Publicado: (2019)

Genome-resolved metagenomics suggests a mutualistic relationship between Mycoplasma and salmonid hosts
por: Rasmussen, Jacob A., et al.
Publicado: (2021)

Insights into rumen microbial biosynthetic gene cluster diversity through genome-resolved metagenomics
por: Anderson, Christopher L., et al.
Publicado: (2021)

Genome-Resolved Metagenomics Reveals Distinct Phosphorus Acquisition Strategies between Soil Microbiomes
por: Wu, Xingjie, et al.
Publicado: (2022)

Genome-resolved metagenomics reveals novel archaeal and bacterial genomes from Amazonian forest and pasture soils
por: Venturini, Andressa M., et al.
Publicado: (2022)

The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis
por: de Mattos-Shipley, Kate M. J., et al.
Publicado: (2018)

Phylotranscriptomics Resolves the Phylogeny of Pooideae and Uncovers Factors for Their Adaptive Evolution
por: Zhang, Lin, et al.
Publicado: (2022)

Carbohydrate Hydrolytic Potential and Redundancy of an Anaerobic Digestion Microbiome Exposed to Acidosis, as Uncovered by Metagenomics
por: Bertucci, Marie, et al.
Publicado: (2019)

Genome assembly of Chiococca alba uncovers key enzymes involved in the biosynthesis of unusual terpenoids
por: Lau, Kin H, et al.
Publicado: (2020)

Diversity, evolution, and classification of virophages uncovered through global metagenomics
por: Paez-Espino, David, et al.
Publicado: (2019)

Genome-resolved metagenomics of eukaryotic populations during early colonization of premature infants and in hospital rooms
por: Olm, Matthew R., et al.
Publicado: (2019)

Genome-resolved metagenomics reveals role of iron metabolism in drought-induced rhizosphere microbiome dynamics
por: Xu, Ling, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8gd5pok5o05luf8h0elq24un9u