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Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams

Traditional studies on the evolution of antibiotic resistance development use approaches that can range from laboratory-based experimental studies, to epidemiological surveillance, to sequencing of clinical isolates. However, evolutionary trajectories also depend on the environment in which selectio...

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Detalles Bibliográficos
Autores principales: Colque, Claudia A., albarracín Orio, Andrea G., Tomatis, Pablo E., Dotta, Gina, Moreno, Diego M., Hedemann, Laura G., Hickman, Rachel A., Sommer, Lea M., Feliziani, Sofía, Moyano, Alejandro J., Bonomo, Robert A., K. Johansen, Helle, Molin, Søren, Vila, Alejandro J., Smania, Andrea M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600753/
https://www.ncbi.nlm.nih.gov/pubmed/36073814
http://dx.doi.org/10.1128/mbio.01663-22