A Human Stem Cell-Derived Brain-Liver Chip for Assessing Blood-Brain-Barrier Permeation of Pharmaceutical Drugs

Significant advancements in the field of preclinical in vitro blood-brain barrier (BBB) models have been achieved in recent years, by developing monolayer-based culture systems towards complex multi-cellular assays. The coupling of those models with other relevant organoid systems to integrate the i...

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Detalles Bibliográficos
Autores principales: Koenig, Leopold, Ramme, Anja Patricia, Faust, Daniel, Mayer, Manuela, Flötke, Tobias, Gerhartl, Anna, Brachner, Andreas, Neuhaus, Winfried, Appelt-Menzel, Antje, Metzger, Marco, Marx, Uwe, Dehne, Eva-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600760/
https://www.ncbi.nlm.nih.gov/pubmed/36291161
http://dx.doi.org/10.3390/cells11203295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600760/
https://www.ncbi.nlm.nih.gov/pubmed/36291161
http://dx.doi.org/10.3390/cells11203295

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