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Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication

Frequent recombination is a hallmark of retrovirus replication. In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health. These recombinants may initially have substantial replication defects...

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Detalles Bibliográficos
Autores principales: Rawson, Jonathan M. O., Nikolaitchik, Olga A., Yoo, Jennifer A., Somoulay, Xayathed, Brown, Matthew A., Mbuntcha Bogni, Franck S., Pathak, Vinay K., Soheilian, Ferri, Slack, Ryan L., Sarafianos, Stefan G., Hu, Wei-Shau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600866/
https://www.ncbi.nlm.nih.gov/pubmed/36036631
http://dx.doi.org/10.1128/mbio.02220-22