Small Molecule Antibiotics Inhibit Distinct Stages of Bacterial Outer Membrane Protein Assembly

Several antibacterial compounds have recently been discovered that potentially inhibit the activity of BamA, an essential subunit of a heterooligomer (the barrel assembly machinery or BAM) that assembles outer membrane proteins (OMPs) in Gram-negative bacteria, but their mode of action is unclear. T...

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Detalles Bibliográficos
Autores principales: Peterson, Janine H., Doyle, Matthew Thomas, Bernstein, Harris D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600915/
https://www.ncbi.nlm.nih.gov/pubmed/36165532
http://dx.doi.org/10.1128/mbio.02286-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600915/
https://www.ncbi.nlm.nih.gov/pubmed/36165532
http://dx.doi.org/10.1128/mbio.02286-22

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