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Design and Synthesis of Thionated Levofloxacin: Insights into a New Generation of Quinolones with Potential Therapeutic and Analytical Applications

Levofloxacin is a widely used fluoroquinolone in several infectious diseases. The structure–activity relationship of levofloxacin has been studied. However, the effect of changing the carbonyl into thiocarbonyl of levofloxacin has not been investigated up to the date of this report. In this work, le...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ali I. M., Abul-Futouh, Hassan, Bourghli, Laurance M. S., Abu-Sini, Mohammad, Sunoqrot, Suhair, Ikhmais, Balqis, Jha, Vibhu, Sarayrah, Qusai, Abulebdah, Dina H., Ismail, Worood H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600924/
https://www.ncbi.nlm.nih.gov/pubmed/36286031
http://dx.doi.org/10.3390/cimb44100316