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Top-Down, Knowledge-Based Genetic Reduction of Yeast Central Carbon Metabolism

Saccharomyces cerevisiae, whose evolutionary past includes a whole-genome duplication event, is characterized by a mosaic genome configuration with substantial apparent genetic redundancy. This apparent redundancy raises questions about the evolutionary driving force for genomic fixation of “minor”...

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Detalles Bibliográficos
Autores principales: Postma, Eline D., Couwenberg, Lucas G. F., van Roosmalen, Roderick N., Geelhoed, Jordi, de Groot, Philip A., Daran-Lapujade, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600970/
https://www.ncbi.nlm.nih.gov/pubmed/36129294
http://dx.doi.org/10.1128/mbio.02970-21