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Herpes Simplex Virus 1 Entry Glycoproteins Form Complexes before and during Membrane Fusion

Herpesviruses—ubiquitous pathogens that cause persistent infections—have some of the most complex cell entry mechanisms. Entry of the prototypical herpes simplex virus 1 (HSV-1) requires coordinated efforts of 4 glycoproteins, gB, gD, gH, and gL. The current model posits that the glycoproteins do no...

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Detalles Bibliográficos
Autores principales: Pataki, Zemplen, Rebolledo Viveros, Andrea, Heldwein, Ekaterina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600979/
https://www.ncbi.nlm.nih.gov/pubmed/35972147
http://dx.doi.org/10.1128/mbio.02039-22