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Plasmodium falciparum and TNF-α Differentially Regulate Inflammatory and Barrier Integrity Pathways in Human Brain Endothelial Cells

Cerebral malaria is a severe complication of Plasmodium falciparum infection characterized by the loss of blood-brain barrier (BBB) integrity, which is associated with brain swelling and mortality in patients. P. falciparum-infected red blood cells and inflammatory cytokines, like tumor necrosis fac...

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Detalles Bibliográficos
Autores principales: Zuniga, Marisol, Gomes, Claudia, Chen, Ze, Martinez, Criseyda, Devlin, Joseph Cooper, Loke, P’ng, Rodriguez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601155/
https://www.ncbi.nlm.nih.gov/pubmed/36036514
http://dx.doi.org/10.1128/mbio.01746-22