Salmonella enterica Infections Are Disrupted by Two Small Molecules That Accumulate within Phagosomes and Differentially Damage Bacterial Inner Membranes

Gram-negative bacteria have a robust cell envelope that excludes or expels many antimicrobial agents. However, during infection, host soluble innate immune factors permeabilize the bacterial outer membrane. We identified two small molecules that exploit outer membrane damage to access the bacterial...

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Detalles Bibliográficos
Autores principales: Villanueva, Joseph A., Crooks, Amy L., Nagy, Toni A., Quintana, Joaquin L. J., Dalebroux, Zachary D., Detweiler, Corrella S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601186/
https://www.ncbi.nlm.nih.gov/pubmed/36135367
http://dx.doi.org/10.1128/mbio.01790-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601186/
https://www.ncbi.nlm.nih.gov/pubmed/36135367
http://dx.doi.org/10.1128/mbio.01790-22

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