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Synovial Macrophages Expression of OX40L Is Required for Follicular Helper T Cells Differentiation in the Joint Microenvironment

Signaling via the OX40/OX40L axis plays a key role in CD4(+) T cell development, and OX40L expression is primarily restricted to antigen-presenting cells (APCs). This study was designed to assess the role of APC-mediated OX40L expression in the context of the development of rheumatoid arthritis (RA)...

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Detalles Bibliográficos
Autores principales: Cai, Xiaoyu, Zhang, Meng, Ren, Fujia, Fei, Weidong, Zhang, Xiao, Zhao, Yunchun, Yao, Yao, Lin, Nengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601235/
https://www.ncbi.nlm.nih.gov/pubmed/36291190
http://dx.doi.org/10.3390/cells11203326