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Direct Detection of Glycated Human Serum Albumin and Hyperglycosylated IgG3 in Serum, by MALDI-ToF Mass Spectrometry, as a Predictor of COVID-19 Severity

The prefusion spike protein of SARS-CoV-2 binds advanced glycation end product (AGE)-glycated human serum albumin (HSA) and a higher mass (hyperglycosylated/glycated) immunoglobulin (Ig) G3, as determined by matrix assisted laser desorption mass spectrometry (MALDI-ToF). We set out to investigate if...

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Detalles Bibliográficos
Autores principales: Iles, Ray K., Iles, Jason K., Lacey, Jonathan, Gardiner, Anna, Zmuidinaite, Raminta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601263/
https://www.ncbi.nlm.nih.gov/pubmed/36292212
http://dx.doi.org/10.3390/diagnostics12102521