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Identification of a Hypomorphic FANCG Variant in Bernese Mountain Dogs

Bernese mountain dogs (BMDs), have an overall cancer incidence of 50%, half of which is comprised of an otherwise rare tumor, histiocytic sarcoma (HS). While recent studies have identified driver mutations in the MAPK pathway, identification of key predisposing genes has been elusive. Studies have i...

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Detalles Bibliográficos
Autores principales: Meek, Katheryn, Yang, Ya-Ting, Takada, Marilia, Parys, Maciej, Richter, Marlee, Engleberg, Alexander I., Thaiwong, Tuddow, Griffin, Rachel L., Schall, Peter Z., Kramer, Alana J., Yuzbasiyan-Gurkan, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601343/
https://www.ncbi.nlm.nih.gov/pubmed/36292578
http://dx.doi.org/10.3390/genes13101693