FOXO3 regulates a common genomic program in aging and glioblastoma stem cells

BACKGROUND: Glioblastoma (GBM) is an aggressive, age-associated malignant glioma that contains populations of cancer stem cells. These glioma stem cells (GSCs) evade therapeutic interventions and repopulate tumors due to their existence in a slowly cycling quiescent state. Although aging is well kno...

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Detalles Bibliográficos
Autores principales: Audesse, Amanda J., Karashchuk, Galina, Gardell, Zachary A., Lakis, Nelli S., Maybury-Lewis, Sun Y., Brown, Abigail K., Leeman, Dena S., Teo, Yee Voan, Neretti, Nicola, Anthony, Douglas C., Brodsky, Alexander S., Webb, Ashley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601604/
https://www.ncbi.nlm.nih.gov/pubmed/36303712
http://dx.doi.org/10.1002/aac2.12043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601604/
https://www.ncbi.nlm.nih.gov/pubmed/36303712
http://dx.doi.org/10.1002/aac2.12043

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