Cargando…

FOXO3 regulates a common genomic program in aging and glioblastoma stem cells

BACKGROUND: Glioblastoma (GBM) is an aggressive, age-associated malignant glioma that contains populations of cancer stem cells. These glioma stem cells (GSCs) evade therapeutic interventions and repopulate tumors due to their existence in a slowly cycling quiescent state. Although aging is well kno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Audesse, Amanda J., Karashchuk, Galina, Gardell, Zachary A., Lakis, Nelli S., Maybury-Lewis, Sun Y., Brown, Abigail K., Leeman, Dena S., Teo, Yee Voan, Neretti, Nicola, Anthony, Douglas C., Brodsky, Alexander S., Webb, Ashley E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601604/ https://www.ncbi.nlm.nih.gov/pubmed/36303712 http://dx.doi.org/10.1002/aac2.12043

Ejemplares similares

Stem cell phenotype predicts therapeutic response in glioblastomas with MGMT promoter methylation
por: Lakis, Nelli S., et al.
Publicado: (2022)

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells
por: Audesse, Amanda J., et al.
Publicado: (2019)

Single-cell transcriptomics of peripheral blood in the aging mouse
por: Teo, Yee Voan, et al.
Publicado: (2023)

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage-and Histone Methylation-Dependent Pathways
por: Ito, Takahiro, et al.
Publicado: (2018)

Cell‐free DNA as a biomarker of aging
por: Teo, Yee Voan, et al.
Publicado: (2018)

Enhancing Lysosomal Activation Restores Neural Stem Cell Function During Aging
por: Audesse, Amanda J, et al.
Publicado: (2018)

Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO
por: Kang, Ping, et al.
Publicado: (2017)

Neuronal functions of FOXO/DAF-16
por: Kim, Sun Y., et al.
Publicado: (2017)

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation and is altered with age
por: Maybury‐Lewis, Sun Y., et al.
Publicado: (2021)

Notch Signaling Mediates Secondary Senescence
por: Teo, Yee Voan, et al.
Publicado: (2019)

Fatty acid binding protein 1 is preferentially lost in microsatellite instable colorectal carcinomas and is immune modulated via the interferon γ pathway
por: Wood, Stephanie M, et al.
Publicado: (2016)

Characterization of the direct targets of FOXO transcription factors throughout evolution
por: Webb, Ashley E., et al.
Publicado: (2016)

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity
por: Post, Stephanie, et al.
Publicado: (2018)

Post-Polio Syndrome Revisited
por: Punsoni, Michael, et al.
Publicado: (2023)

FOXO3 Promotes Quiescence in Adult Muscle Stem Cells during the Process of Self-Renewal
por: Gopinath, Suchitra D., et al.
Publicado: (2014)

Evaluation of a web-based portal to improve resident education by neonatology fellows
por: Lakshmanan, Ashwini, et al.
Publicado: (2014)

FOXO1 is crucial in glioblastoma cell tumorigenesis and regulates the expression of SIRT1 to suppress senescence in the brain
por: Yan, Han, et al.
Publicado: (2018)

The FOXO1 inhibitor AS1842856 triggers apoptosis in glioblastoma multiforme and basal‐like breast cancer cells
por: Flores, David, et al.
Publicado: (2023)

FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors
por: Peña-Pérez, Lucía, et al.
Publicado: (2022)

Methylation by Set9 modulates FoxO3 stability and transcriptional activity
por: Calnan, Daniel R., et al.
Publicado: (2012)

Multimedia Information Extraction
por: Maybury, Mark T
Publicado: (2012)

Intracranial tuberculoma: a rare complication of extrapulmonary tuberculosis. Illustrative case
por: Letchuman, Vijay, et al.
Publicado: (2022)

Genetic Association Analysis of Common Variants in FOXO3 Related to Longevity in a Chinese Population
por: Lin, Rong, et al.
Publicado: (2016)

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
por: Martins, Rute, et al.
Publicado: (2015)

Functional Precision Oncology: The Next Frontier to Improve Glioblastoma Outcome?
por: Panovska, Dena, et al.
Publicado: (2022)

Human macrophages engineered to secrete a bispecific T cell engager support antigen-dependent T cell responses to glioblastoma
por: Gardell, Jennifer L, et al.
Publicado: (2020)

FOXOs: masters of the equilibrium
por: Gui, Tianshu, et al.
Publicado: (2021)

FOXO family isoforms
por: Santos, Bruno F., et al.
Publicado: (2023)

FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development
por: Luu, Thuy T., et al.
Publicado: (2022)

Exon expression profiling reveals stimulus-mediated exon use in neural cells
por: McKee, Adrienne E, et al.
Publicado: (2007)

Despite disorganized synapse structure, Th2 cells maintain directional delivery of CD40L to antigen-presenting B cells
por: Gardell, Jennifer L., et al.
Publicado: (2017)

Targeting FoxO1 with AS1842856 Suppresses Adipogenesis
por: Zou, Peng, et al.
Publicado: (2014)

FOXO1 promotes the expression of canonical WNT target genes in examined basal‐like breast and glioblastoma multiforme cancer cells
por: Pintor, Shania, et al.
Publicado: (2023)

Loss of foxo rescues stem cell aging in Drosophila germ line
por: Artoni, Filippo, et al.
Publicado: (2017)

Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle
por: Lundell, Leonidas S., et al.
Publicado: (2018)

Tissue-Specific Metabolic Regulation of FOXO-Binding Protein: FOXO Does Not Act Alone
por: Kodani, Noriko, et al.
Publicado: (2020)

The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis
por: Lallemand, François, et al.
Publicado: (2020)

Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma
por: Park, Soon Young, et al.
Publicado: (2016)

Development of a computational strategy to compare repetitive element enrichment between experimental conditions from high-throughput sequencing datasets
por: Criscione, Steven, et al.
Publicado: (2012)

A program to correlate the information from three views of a spark chamber
por: Maybury, R, et al.
Publicado: (1976)

Cannot write session to /tmp/vufind_sessions/sess_47ph9o770q983eaumgealv4ril