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Episomes and Transposases—Utilities to Maintain Transgene Expression from Nonviral Vectors

The efficient delivery and stable transgene expression are critical for applications in gene therapy. While carefully selected and engineered viral vectors allowed for remarkable clinical successes, they still bear significant safety risks. Thus, nonviral vectors are a sound alternative and avoid ge...

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Detalles Bibliográficos
Autores principales: Kreppel, Florian, Hagedorn, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601623/
https://www.ncbi.nlm.nih.gov/pubmed/36292757
http://dx.doi.org/10.3390/genes13101872