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Episomes and Transposases—Utilities to Maintain Transgene Expression from Nonviral Vectors
The efficient delivery and stable transgene expression are critical for applications in gene therapy. While carefully selected and engineered viral vectors allowed for remarkable clinical successes, they still bear significant safety risks. Thus, nonviral vectors are a sound alternative and avoid ge...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601623/ https://www.ncbi.nlm.nih.gov/pubmed/36292757 http://dx.doi.org/10.3390/genes13101872 |