Cargando…

Projection of Expression Profiles to Transcription Factor Activity Space Provides Added Information

Acute myeloid leukemia (AML) is an aggressive type of leukemia, characterized by the accumulation of highly proliferative blasts with a disrupted myeloid differentiation program. Current treatments are ineffective for most patients, partly due to the genetic heterogeneity of AML. This is driven by g...

Descripción completa

Detalles Bibliográficos
Autores principales: Bornshten, Rut, Danilenko, Michael, Rubin, Eitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601664/
https://www.ncbi.nlm.nih.gov/pubmed/36292704
http://dx.doi.org/10.3390/genes13101819